Trust Me follows flailing Hollywood agent Howard, who seemingly strikes gold after signing the next big child star. What results is an unexpected ride through the nasty inner workings of Hollywood, as Howard desperately tries to make it in an industry that has no interest in recognizing his bumbling but ultimately genuine nature.
A team of trained secret agent animals, guinea pigs Darwin, Juarez, Blaster, mole Speckles, and fly Mooch takes on a mission for the US government to stop evil Leonard Saber, who plans to destroy the world with household appliances. But the government shuts them down and they are sentenced to a pet shop. Can they escape to defeat the villain and save the world?